Cyclobenzaprine Flexeril Side Effects & Interactions

Drowsiness is the most commonly reported side effect in studies, occurring in up to 38% (38 out of 100) of people. Avoid or limit the use of alcohol or other sedating medicines while being treated with cyclobenzaprine. Also avoid driving, operating machinery, or other hazardous activities until you know how cyclobenzaprine affects you. Some medicines can interact with cyclobenzaprine and cause a serious condition called serotonin syndrome. Ask your doctor before making any changes in how or when you take your medications. In patients with CNS depression, early intubation is advised because of the potential for abrupt deterioration.

  • Both drugs are skeletal muscle relaxants or antispasmodic agents, but they contain different active ingredients.
  • Check with your physician for additional information about side effects.
  • Cyclobenzaprine is used to help relax certain muscles in your body.

For most patients, the recommended starting dose is 5 mg three times a day. Based on how the patient is responding, the dose may be increased to either 7.5 mg or 10 mg three times a day. In case of acute cyclobenzaprine overdose, emergency medicine physicians and triage nurses should stabilize the patient. If EKG demonstrates QRS prolongation, the clinician should initiate sodium bicarbonate therapy.

Cyclobenzaprine Tablets

Examples of drugs that can cause interactions with cyclobenzaprine are listed below. Also, methocarbamol and cyclobenzaprine are not recommended in pregnant women, elderly adults, and young children. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Flexeril is usually taken once daily for only 2 or 3 weeks. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. Analysis of the data from controlled studies shows that FLEXERIL produces clinical improvement whether or not sedation occurs. It is not known whether this drug is excreted in human milk.

Clinical monitoring

Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication. Using Flexeril with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

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Cyclobenzaprine is a centrally acting skeletal muscle relaxant structurally related to tricyclic antidepr[7]essants. Cyclobenzaprine relieves skeletal muscle spasms of local origin without interfering with muscle function. In preclinical research, cyclobenzaprine reduced skeletal muscle hyperactivity.

It is not controlled under the Controlled Substances Act (CSA), either. However, since Flexeril has properties that suppress pain, people may overuse it to amplify those feelings. The activity of Flexeril that depresses the Central Nervous System (CNS) makes it potentially addictive and dangerous. Another rare side effect is an allergic reaction to the drug, manifested by hives and trouble breathing.

Keep a list of all your healthcare treatments (prescription and OTC medications, vitamins, supplements, alternative therapy regimens) and provide this list to your doctor. Talk with your healthcare provider before starting any new treatment. If you have a medical emergency at any point, please immediately contact 911 or seek emergency in-person medical care. Cyclobenzaprine can increase the effects of CNS depressants, such as alcohol, opioids, allergy medications, and sleeping pills. This enables the provider to evaluate for any potential interactions and helps them keep the patient safe.® is not available to customers or patients who are located outside of the United States or U.S. territories. If you become pregnant or are breastfeeding, please stop treatment and notify us immediately or talk to a doctor in-person. For a thorough understanding of potential side effects, please consult a physician.

This is especially true if someone has been engaging in polydrug use with cyclobenzaprine and other substances. Another telltale sign of Flexeril addiction is abusing the medication in combination with another substance to produce a greater sense of euphoria. can you drive with flexeril Alcohol is commonly abused alongside muscle relaxers like Flexeril because the substances amplify each others’ effects, causing the individual to experience a more intense sedation or high. It is unknown if this medication passes into breast milk.